53BP1 Supports Immunoglobulin Class Switch Recombination Independently of Its DNA Double-Strand Break End Protection Function

Class switch recombination (CSR) is a DNA recombination reaction that diversifies the effector functions of antibodies. CSR occurs via the formation and non-homologous end joining (NHEJ) repair of programmed DNA double-strand breaks (DSBs) at the immunoglobulin heavy chain locus. The DNA repair fact...

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Detalles Bibliográficos
Autores principales: Sundaravinayagam, Devakumar, Rahjouei, Ali, Andreani, Matteo, Tupiņa, Dagnija, Balasubramanian, Sandhya, Saha, Tannishtha, Delgado-Benito, Verónica, Coralluzzo, Violeta, Daumke, Oliver, Di Virgilio, Michela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693562/
https://www.ncbi.nlm.nih.gov/pubmed/31390554
http://dx.doi.org/10.1016/j.celrep.2019.06.035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693562/
https://www.ncbi.nlm.nih.gov/pubmed/31390554
http://dx.doi.org/10.1016/j.celrep.2019.06.035

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