Memory CD4 T cell-derived IL-2 synergizes with viral infection to exacerbate lung inflammation

Defining the most penetrating correlates of protective memory T cells is key for designing improved vaccines and T cell therapies. Here, we evaluate how interleukin (IL-2) production by memory CD4 T cells, a widely held indicator of their protective potential, impacts immune responses against murine...

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Detalles Bibliográficos
Autores principales: McKinstry, K. Kai, Alam, Fahmida, Flores-Malavet, Valeria, Nagy, Mate Z., Sell, Stewart, Cooper, Andrea M., Swain, Susan L., Strutt, Tara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693742/
https://www.ncbi.nlm.nih.gov/pubmed/31412088
http://dx.doi.org/10.1371/journal.ppat.1007989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693742/
https://www.ncbi.nlm.nih.gov/pubmed/31412088
http://dx.doi.org/10.1371/journal.ppat.1007989

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