Engineered collagen-binding serum albumin as a drug conjugate carrier for cancer therapy

Serum albumin (SA) is used as a carrier to deliver cytotoxic agents to tumors via passive targeting. To further improve SA’s tumor targeting capacity, we sought to develop an approach to retain SA-drug conjugates within tumors through a combination of passive and active targeting. SA was recombinant...

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Detalles Bibliográficos
Autores principales: Sasaki, Koichi, Ishihara, Jun, Ishihara, Ako, Miura, Risako, Mansurov, Aslan, Fukunaga, Kazuto, Hubbell, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693903/
https://www.ncbi.nlm.nih.gov/pubmed/31453327
http://dx.doi.org/10.1126/sciadv.aaw6081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693903/
https://www.ncbi.nlm.nih.gov/pubmed/31453327
http://dx.doi.org/10.1126/sciadv.aaw6081

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