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The histone code reader PHD finger protein 7 controls sex-linked disparities in gene expression and malignancy in Drosophila

The notable male predominance across many human cancer types remains unexplained. Here, we show that Drosophila l(3)mbt brain tumors are more invasive and develop as malignant neoplasms more often in males than in females. By quantitative proteomics, we have identified a signature of proteins that a...

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Detalles Bibliográficos
Autores principales: Molnar, Cristina, Heinen, Jan Peter, Reina, Jose, Llamazares, Salud, Palumbo, Emilio, Breschi, Alessandra, Gay, Marina, Villarreal, Laura, Vilaseca, Marta, Pollarolo, Giulia, Gonzalez, Cayetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693905/
https://www.ncbi.nlm.nih.gov/pubmed/31453329
http://dx.doi.org/10.1126/sciadv.aaw7965