Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank

Genotype-by-environment interaction (GEI) is a fundamental component in understanding complex trait variation. However, it remains challenging to identify genetic variants with GEI effects in humans largely because of the small effect sizes and the difficulty of monitoring environmental fluctuations...

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Detalles Bibliográficos
Autores principales: Wang, Huanwei, Zhang, Futao, Zeng, Jian, Wu, Yang, Kemper, Kathryn E., Xue, Angli, Zhang, Min, Powell, Joseph E., Goddard, Michael E., Wray, Naomi R., Visscher, Peter M., McRae, Allan F., Yang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693916/
https://www.ncbi.nlm.nih.gov/pubmed/31453325
http://dx.doi.org/10.1126/sciadv.aaw3538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693916/
https://www.ncbi.nlm.nih.gov/pubmed/31453325
http://dx.doi.org/10.1126/sciadv.aaw3538

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