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SBP2 deficiency in adipose tissue macrophages drives insulin resistance in obesity

Proinflammatory activation and accumulation of adipose tissue macrophages (ATMs) are associated with increased risk of insulin resistance in obesity. Here, we described the previously unidentified role of selenocysteine insertion sequence–binding protein 2 (SBP2) in maintaining insulin sensitivity i...

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Detalles Bibliográficos
Autores principales: Wang, Ning, Tan, Hor-Yue, Li, Sha, Wang, Di, Xu, Yu, Zhang, Cheng, Xia, Wen, Che, Chi-Ming, Feng, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693917/
https://www.ncbi.nlm.nih.gov/pubmed/31453320
http://dx.doi.org/10.1126/sciadv.aav0198