Driving Recursive Dehydration by P(III)/P(V) Catalysis: Annulation of Amines and Carboxylic Acids by Sequential C–N and C–C Bond Formation

[Image: see text] A method for the annulation of amines and carboxylic acids to form pharmaceutically relevant azaheterocycles via organophosphorus P(III)/P(V) redox catalysis is reported. The method employs a phosphetane catalyst together with a mild bromenium oxidant and terminal hydrosilane reduc...

Descripción completa

Detalles Bibliográficos
Autores principales: Lecomte, Morgan, Lipshultz, Jeffrey M., Kim-Lee, Shin-Ho, Li, Gen, Radosevich, Alexander T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693942/
https://www.ncbi.nlm.nih.gov/pubmed/31345031
http://dx.doi.org/10.1021/jacs.9b06277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693942/
https://www.ncbi.nlm.nih.gov/pubmed/31345031
http://dx.doi.org/10.1021/jacs.9b06277

Ejemplares similares