Candidate gene analyses for acute pain and morphine analgesia after pediatric day surgery: African American versus European Caucasian ancestry and dose prediction limits

Acute pain and opioid analgesia demonstrate inter-individual variability and polygenic influence. In 241 children of African American and 277 of European Caucasian ancestry, we sought to replicate select candidate gene associations with morphine dose and postoperative pain and then to estimate dose...

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Detalles Bibliográficos
Autores principales: Li, Jin, Wei, Zhi, Zhang, Jie, Hakonarson, Hakon, Cook-Sather, Scott D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693985/
https://www.ncbi.nlm.nih.gov/pubmed/30760877
http://dx.doi.org/10.1038/s41397-019-0074-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693985/
https://www.ncbi.nlm.nih.gov/pubmed/30760877
http://dx.doi.org/10.1038/s41397-019-0074-4

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