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Postovulatory ageing modifies sperm-induced Ca(2+) oscillations in mouse oocytes through a conditions-dependent, multi-pathway mechanism

Postovulatory ageing of mammalian oocytes occurs between their ovulation and fertilization and has been shown to decrease their developmental capabilities. Aged oocytes display numerous abnormalities, including altered Ca(2+) signalling. Fertilization-induced Ca(2+) oscillations are essential for ac...

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Detalles Bibliográficos
Autores principales: Szpila, Marcin, Walewska, Agnieszka, Sabat-Pośpiech, Dorota, Strączyńska, Patrycja, Ishikawa, Takao, Milewski, Robert, Szczepańska, Katarzyna, Ajduk, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694115/
https://www.ncbi.nlm.nih.gov/pubmed/31413272
http://dx.doi.org/10.1038/s41598-019-48281-3