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Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 expression

Breast cancer stem cells (BCSCs) are unique in their ability to undergo unlimited self-renewal, an essential process in breast cancer recurrence following metastatic dormancy. Emergent metastatic lesions were subjected to microarray analysis, which identified 6-phosphofructo-2-kinase/fructose-2,6-bi...

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Detalles Bibliográficos
Autores principales: La Belle Flynn, Alyssa, Calhoun, Benjamin C., Sharma, Arishya, Chang, Jenny C., Almasan, Alexandru, Schiemann, William P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694140/
https://www.ncbi.nlm.nih.gov/pubmed/31413316
http://dx.doi.org/10.1038/s41467-019-11640-9