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Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 expression
Breast cancer stem cells (BCSCs) are unique in their ability to undergo unlimited self-renewal, an essential process in breast cancer recurrence following metastatic dormancy. Emergent metastatic lesions were subjected to microarray analysis, which identified 6-phosphofructo-2-kinase/fructose-2,6-bi...
Autores principales: | La Belle Flynn, Alyssa, Calhoun, Benjamin C., Sharma, Arishya, Chang, Jenny C., Almasan, Alexandru, Schiemann, William P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694140/ https://www.ncbi.nlm.nih.gov/pubmed/31413316 http://dx.doi.org/10.1038/s41467-019-11640-9 |
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