PTPσ inhibitors promote hematopoietic stem cell regeneration

Receptor type protein tyrosine phosphatase-sigma (PTPσ) is primarily expressed by adult neurons and regulates neural regeneration. We recently discovered that PTPσ is also expressed by hematopoietic stem cells (HSCs). Here, we describe small molecule inhibitors of PTPσ that promote HSC regeneration...

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Detalles Bibliográficos
Autores principales: Zhang, Yurun, Roos, Martina, Himburg, Heather, Termini, Christina M., Quarmyne, Mamle, Li, Michelle, Zhao, Liman, Kan, Jenny, Fang, Tiancheng, Yan, Xiao, Pohl, Katherine, Diers, Emelyne, Jin Gim, Hyo, Damoiseaux, Robert, Whitelegge, Julian, McBride, William, Jung, Michael E., Chute, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694155/
https://www.ncbi.nlm.nih.gov/pubmed/31413255
http://dx.doi.org/10.1038/s41467-019-11490-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694155/
https://www.ncbi.nlm.nih.gov/pubmed/31413255
http://dx.doi.org/10.1038/s41467-019-11490-5

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