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Variable ability of rapid tests to detect Mycobacterium tuberculosis rpoB mutations conferring phenotypically occult rifampicin resistance

We compared the ability of commercial and non-commercial, phenotypic and genotypic rapid drug susceptibility tests (DSTs) to detect rifampicin resistance (RR)-conferring ‘disputed’ mutations frequently missed by Mycobacterium Growth Indicator Tube (MGIT), namely L430P, D435Y, L452P, and I491F. Strai...

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Detalles Bibliográficos
Autores principales: Torrea, Gabriela, Ng, Kamela C. S., Van Deun, Armand, André, Emmanuel, Kaisergruber, Justine, Ssengooba, Willy, Desmaretz, Christel, Gabriels, Siemon, Driesen, Michèle, Diels, Maren, Asnong, Sylvie, Fissette, Kristina, Gumusboga, Mourad, Rigouts, Leen, Affolabi, Dissou, Joloba, Moses, De Jong, Bouke C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694172/
https://www.ncbi.nlm.nih.gov/pubmed/31413308
http://dx.doi.org/10.1038/s41598-019-48401-z