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Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration
BACKGROUND & AIMS: Excess liver iron content is common and is linked to the risk of hepatic and extrahepatic diseases. We aimed to identify genetic variants influencing liver iron content and use genetics to understand its link to other traits and diseases. METHODS: First, we performed a genome-...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694204/ https://www.ncbi.nlm.nih.gov/pubmed/31226389 http://dx.doi.org/10.1016/j.jhep.2019.05.032 |