Let‐7a‐regulated translational readthrough of mammalian AGO1 generates a microRNA pathway inhibitor

Translational readthrough generates proteins with extended C‐termini, which often possess distinct properties. Here, we have used various reporter assays to demonstrate translational readthrough of AGO1 mRNA. Analysis of ribosome profiling data and mass spectrometry data provided additional evidence...

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Detalles Bibliográficos
Autores principales: Singh, Anumeha, Manjunath, Lekha E, Kundu, Pradipta, Sahoo, Sarthak, Das, Arpan, Suma, Harikumar R, Fox, Paul L, Eswarappa, Sandeep M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694283/
https://www.ncbi.nlm.nih.gov/pubmed/31330067
http://dx.doi.org/10.15252/embj.2018100727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694283/
https://www.ncbi.nlm.nih.gov/pubmed/31330067
http://dx.doi.org/10.15252/embj.2018100727

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