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Let‐7a‐regulated translational readthrough of mammalian AGO1 generates a microRNA pathway inhibitor
Translational readthrough generates proteins with extended C‐termini, which often possess distinct properties. Here, we have used various reporter assays to demonstrate translational readthrough of AGO1 mRNA. Analysis of ribosome profiling data and mass spectrometry data provided additional evidence...
Autores principales: | Singh, Anumeha, Manjunath, Lekha E, Kundu, Pradipta, Sahoo, Sarthak, Das, Arpan, Suma, Harikumar R, Fox, Paul L, Eswarappa, Sandeep M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694283/ https://www.ncbi.nlm.nih.gov/pubmed/31330067 http://dx.doi.org/10.15252/embj.2018100727 |
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