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The Influence of Cerebrospinal Fluid Abnormalities and APOE 4 on PHF-Tau Protein: Evidence From Voxel Analysis and Graph Theory

Mild cognitive impairment (MCI) is a transitional state between the cognitive changes in normal aging and Alzheimer’s disease (AD), which induces abnormalities in specific brain regions. Previous studies showed that paired helical filaments Tau (PHF-Tau) protein is a potential pathogenic protein whi...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Yao, Zhijun, Yu, Yue, Fu, Yu, Zou, Ying, Hu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694441/
https://www.ncbi.nlm.nih.gov/pubmed/31440157
http://dx.doi.org/10.3389/fnagi.2019.00208