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Gonadal Failure Is Common in Long-Term Survivors of Childhood High-Risk Neuroblastoma Treated With High-Dose Chemotherapy and Autologous Stem Cell Rescue

Background: Neuroblastoma is the most common extra-cranial solid tumor in children. Intensive therapy including autologous stem-cell transplantation (HSCT) has improved the poor prognosis of high-risk neuroblastoma (HR-NBL) but may impair gonadal function. Objectives: To investigate the gonadal func...

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Detalles Bibliográficos
Autores principales: Utriainen, Pauliina, Suominen, Anu, Mäkitie, Outi, Jahnukainen, Kirsi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694459/
https://www.ncbi.nlm.nih.gov/pubmed/31440211
http://dx.doi.org/10.3389/fendo.2019.00555