Reduction of Mitophagy-Related Oxidative Stress and Preservation of Mitochondria Function Using Melatonin Therapy in an HT22 Hippocampal Neuronal Cell Model of Glutamate-Induced Excitotoxicity

Recent evidence indicates that autophagy-mediated mitochondrial homeostasis is crucial for oxidative stress-related brain damage and repair. The highest concentration of melatonin is in the mitochondria of cells, and melatonin exhibits well-known antioxidant properties. We investigated the impact an...

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Detalles Bibliográficos
Autores principales: Wang, Dan-dan, Jin, Mei-fang, Zhao, Dong-jing, Ni, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694460/
https://www.ncbi.nlm.nih.gov/pubmed/31440210
http://dx.doi.org/10.3389/fendo.2019.00550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694460/
https://www.ncbi.nlm.nih.gov/pubmed/31440210
http://dx.doi.org/10.3389/fendo.2019.00550

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