Efficient in vivo bone formation by BMP-2 engineered human mesenchymal stem cells encapsulated in a projection stereolithographically fabricated hydrogel scaffold

BACKGROUND: Stem cell-based bone tissue engineering shows promise for bone repair but faces some challenges, such as insufficient osteogenesis and limited architecture flexibility of the cell-delivery scaffold. METHODS: In this study, we first used lentiviral constructs to transduce ex vivo human bo...

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Detalles Bibliográficos
Autores principales: Lin, Hang, Tang, Ying, Lozito, Thomas P., Oyster, Nicholas, Wang, Bing, Tuan, Rocky S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694509/
https://www.ncbi.nlm.nih.gov/pubmed/31412905
http://dx.doi.org/10.1186/s13287-019-1350-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694509/
https://www.ncbi.nlm.nih.gov/pubmed/31412905
http://dx.doi.org/10.1186/s13287-019-1350-6

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