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Apigenin inhibits fibroblast proliferation and reduces epidural fibrosis by regulating Wnt3a/β-catenin signaling pathway

BACKGROUND: Failed back surgery syndrome (FBSS) is a common complication after the laminectomy. Epidural fibrosis is the major cause of lower back pain and other complications. Numerous studies have shown that apigenin (API) could treat various fibrotic diseases by regulating various signaling pathw...

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Detalles Bibliográficos
Autores principales: Jiao, Rui, Chen, Hui, Wan, Qi, Zhang, Xiaobo, Dai, Jihang, Li, Xiaolei, Yan, Lianqi, Sun, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694561/
https://www.ncbi.nlm.nih.gov/pubmed/31412883
http://dx.doi.org/10.1186/s13018-019-1305-8