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Apigenin inhibits fibroblast proliferation and reduces epidural fibrosis by regulating Wnt3a/β-catenin signaling pathway
BACKGROUND: Failed back surgery syndrome (FBSS) is a common complication after the laminectomy. Epidural fibrosis is the major cause of lower back pain and other complications. Numerous studies have shown that apigenin (API) could treat various fibrotic diseases by regulating various signaling pathw...
Autores principales: | Jiao, Rui, Chen, Hui, Wan, Qi, Zhang, Xiaobo, Dai, Jihang, Li, Xiaolei, Yan, Lianqi, Sun, Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694561/ https://www.ncbi.nlm.nih.gov/pubmed/31412883 http://dx.doi.org/10.1186/s13018-019-1305-8 |
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