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The effect of medium supplementation and serial passaging on the transcriptome of human adipose-derived stromal cells expanded in vitro

BACKGROUND: For adipose-derived stromal cells (ASCs) to be safe for use in the clinical setting, they need to be prepared using good manufacturing practices (GMPs). Fetal bovine serum (FBS), used to expand ASCs in vitro in some human clinical trials, runs the risk of xenoimmunization and zoonotic di...

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Detalles Bibliográficos
Autores principales: Dessels, Carla, Ambele, Melvin A., Pepper, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694630/
https://www.ncbi.nlm.nih.gov/pubmed/31412930
http://dx.doi.org/10.1186/s13287-019-1370-2