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The effect of medium supplementation and serial passaging on the transcriptome of human adipose-derived stromal cells expanded in vitro
BACKGROUND: For adipose-derived stromal cells (ASCs) to be safe for use in the clinical setting, they need to be prepared using good manufacturing practices (GMPs). Fetal bovine serum (FBS), used to expand ASCs in vitro in some human clinical trials, runs the risk of xenoimmunization and zoonotic di...
Autores principales: | Dessels, Carla, Ambele, Melvin A., Pepper, Michael S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694630/ https://www.ncbi.nlm.nih.gov/pubmed/31412930 http://dx.doi.org/10.1186/s13287-019-1370-2 |
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