Tubeimoside-I sensitizes colorectal cancer cells to chemotherapy by inducing ROS-mediated impaired autophagolysosomes accumulation

BACKGROUND: Tubeimoside-I (TBM), a plant-derived bioactive compound, shows antitumor activity in different tumors and can enhance the efficacy of chemotherapeutic agents. However, the detail mechanism underlying remains to be elucidated. METHODS: The cytotoxic potential of TBM towards CRC cells was...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Jianghong, Dou, Xiaoyun, Zhou, Jing, Xiong, Yuanfeng, Mo, Ling, Li, Longhao, Lei, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694658/
https://www.ncbi.nlm.nih.gov/pubmed/31412953
http://dx.doi.org/10.1186/s13046-019-1355-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694658/
https://www.ncbi.nlm.nih.gov/pubmed/31412953
http://dx.doi.org/10.1186/s13046-019-1355-0

Ejemplares similares