AlleleAnalyzer: a tool for personalized and allele-specific sgRNA design

The CRISPR/Cas system is a highly specific genome editing tool capable of distinguishing alleles differing by even a single base pair. Target sites might carry genetic variations that are not distinguishable by sgRNA designing tools based on one reference genome. AlleleAnalyzer is an open-source sof...

Descripción completa

Detalles Bibliográficos
Autores principales: Keough, Kathleen C., Lyalina, Svetlana, Olvera, Michael P., Whalen, Sean, Conklin, Bruce R., Pollard, Katherine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694686/
https://www.ncbi.nlm.nih.gov/pubmed/31416467
http://dx.doi.org/10.1186/s13059-019-1783-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694686/
https://www.ncbi.nlm.nih.gov/pubmed/31416467
http://dx.doi.org/10.1186/s13059-019-1783-3

Ejemplares similares