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AlleleAnalyzer: a tool for personalized and allele-specific sgRNA design

The CRISPR/Cas system is a highly specific genome editing tool capable of distinguishing alleles differing by even a single base pair. Target sites might carry genetic variations that are not distinguishable by sgRNA designing tools based on one reference genome. AlleleAnalyzer is an open-source sof...

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Detalles Bibliográficos
Autores principales:	Keough, Kathleen C., Lyalina, Svetlana, Olvera, Michael P., Whalen, Sean, Conklin, Bruce R., Pollard, Katherine S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694686/ https://www.ncbi.nlm.nih.gov/pubmed/31416467 http://dx.doi.org/10.1186/s13059-019-1783-3

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