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Thrombomodulin in disseminated intravascular coagulation and other critical conditions—a multi-faceted anticoagulant protein with therapeutic potential

Thrombomodulin plays a vital role in maintaining intravascular patency due to its anticoagulant, antiinflammatory, and cytoprotective properties. However, under pathological conditions such as sepsis and systemic inflammation, endothelial thrombomodulin expression is downregulated and its function i...

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Detalles Bibliográficos
Autores principales: Ito, Takashi, Thachil, Jecko, Asakura, Hidesaku, Levy, Jerrold H., Iba, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694689/
https://www.ncbi.nlm.nih.gov/pubmed/31416465
http://dx.doi.org/10.1186/s13054-019-2552-0