A Phase Ib Study of the Combination of Personalized Autologous Dendritic Cell Vaccine, Aspirin, and Standard of Care Adjuvant Chemotherapy Followed by Nivolumab for Resected Pancreatic Adenocarcinoma—A Proof of Antigen Discovery Feasibility in Three Patients

Despite the promising therapeutic effects of immune checkpoint blockade (ICB), most patients with solid tumors treated with anti-PD-1/PD-L1 monotherapy do not achieve objective responses, with most tumor regressions being partial rather than complete. It is hypothesized that the absence of pre-exist...

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Detalles Bibliográficos
Autores principales: Bassani-Sternberg, Michal, Digklia, Antonia, Huber, Florian, Wagner, Dorothea, Sempoux, Christine, Stevenson, Brian J., Thierry, Anne-Christine, Michaux, Justine, Pak, HuiSong, Racle, Julien, Boudousquie, Caroline, Balint, Klara, Coukos, George, Gfeller, David, Martin Lluesma, Silvia, Harari, Alexandre, Demartines, Nicolas, Kandalaft, Lana E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694698/
https://www.ncbi.nlm.nih.gov/pubmed/31440238
http://dx.doi.org/10.3389/fimmu.2019.01832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694698/
https://www.ncbi.nlm.nih.gov/pubmed/31440238
http://dx.doi.org/10.3389/fimmu.2019.01832

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