Using the MR-Base platform to investigate risk factors and drug targets for thousands of phenotypes

Mendelian randomization (MR) estimates the causal effect of exposures on outcomes by exploiting genetic variation to address confounding and reverse causation. This method has a broad range of applications, including investigating risk factors and appraising potential targets for intervention. MR-Ba...

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Detalles Bibliográficos
Autores principales: Walker, Venexia M, Davies, Neil M, Hemani, Gibran, Zheng, Jie, Haycock, Philip C, Gaunt, Tom R, Davey Smith, George, Martin, Richard M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Software Tool Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694718/
https://www.ncbi.nlm.nih.gov/pubmed/31448343
http://dx.doi.org/10.12688/wellcomeopenres.15334.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694718/
https://www.ncbi.nlm.nih.gov/pubmed/31448343
http://dx.doi.org/10.12688/wellcomeopenres.15334.2

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