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Prediction of deleterious single nucleotide polymorphisms and their effect on the sequence and structure of the human CCND1 gene

OBJECTIVE: The CCND1 gene expresses a protein, G1/S-specific cyclin, that regulates the G1/S transition in the cell cycle and also inhibits retinoblastoma (RB) proteins. Overexpression or rearrangements of this gene can result in various tumours. This study aimed to identify possible deleterious non...

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Detalles Bibliográficos
Autores principales: Yoganarasimha, Bharath, Chandramohan, Vivek, Krishna Murthy, Thirupathihalli P., Gangadharappa, Bhavya S., Siddaiah, Gowrishankar B., Hanumanthappa, Makari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taibah University 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695066/
https://www.ncbi.nlm.nih.gov/pubmed/31435243
http://dx.doi.org/10.1016/j.jtumed.2016.07.009