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Prediction of deleterious single nucleotide polymorphisms and their effect on the sequence and structure of the human CCND1 gene
OBJECTIVE: The CCND1 gene expresses a protein, G1/S-specific cyclin, that regulates the G1/S transition in the cell cycle and also inhibits retinoblastoma (RB) proteins. Overexpression or rearrangements of this gene can result in various tumours. This study aimed to identify possible deleterious non...
Autores principales: | Yoganarasimha, Bharath, Chandramohan, Vivek, Krishna Murthy, Thirupathihalli P., Gangadharappa, Bhavya S., Siddaiah, Gowrishankar B., Hanumanthappa, Makari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taibah University
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695066/ https://www.ncbi.nlm.nih.gov/pubmed/31435243 http://dx.doi.org/10.1016/j.jtumed.2016.07.009 |
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