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Dysregulation of M segment gene expression contributes to influenza A virus host restriction

The M segment of the 2009 pandemic influenza A virus (IAV) has been implicated in its emergence into human populations. To elucidate the genetic contributions of the M segment to host adaptation, and the underlying mechanisms, we examined a panel of isogenic viruses that carry avian- or human-derive...

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Detalles Bibliográficos
Autores principales: Calderon, Brenda M., Danzy, Shamika, Delima, Gabrielle K., Jacobs, Nathan T., Ganti, Ketaki, Hockman, Megan R., Conn, Graeme L., Lowen, Anice C., Steel, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695095/
https://www.ncbi.nlm.nih.gov/pubmed/31415678
http://dx.doi.org/10.1371/journal.ppat.1007892