Cargando…

Dysregulation of M segment gene expression contributes to influenza A virus host restriction

The M segment of the 2009 pandemic influenza A virus (IAV) has been implicated in its emergence into human populations. To elucidate the genetic contributions of the M segment to host adaptation, and the underlying mechanisms, we examined a panel of isogenic viruses that carry avian- or human-derive...

Descripción completa

Detalles Bibliográficos
Autores principales:	Calderon, Brenda M., Danzy, Shamika, Delima, Gabrielle K., Jacobs, Nathan T., Ganti, Ketaki, Hockman, Megan R., Conn, Graeme L., Lowen, Anice C., Steel, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695095/ https://www.ncbi.nlm.nih.gov/pubmed/31415678 http://dx.doi.org/10.1371/journal.ppat.1007892

Ejemplares similares

Influenza A virus coinfection dynamics are shaped by distinct virus-virus interactions within and between cells
por: Delima, Gabrielle K., et al.
Publicado: (2023)

Human OAS1 activation is highly dependent on both RNA sequence and context of activating RNA motifs
por: Schwartz, Samantha L, et al.
Publicado: (2020)

Rab11a mediates cell-cell spread and reassortment of influenza A virus genomes via tunneling nanotubes
por: Ganti, Ketaki, et al.
Publicado: (2021)

Beneficial effects of cellular coinfection resolve inefficiency in influenza A virus transcription
por: Shartouny, Jessica R., et al.
Publicado: (2022)

Timing of exposure is critical in a highly sensitive model of SARS-CoV-2 transmission
por: Ganti, Ketaki, et al.
Publicado: (2022)

Influenza Virus Reassortment Occurs with High Frequency in the Absence of Segment Mismatch
por: Marshall, Nicolle, et al.
Publicado: (2013)

Avian Influenza A Viruses Reassort and Diversify Differently in Mallards and Mammals
por: Ganti, Ketaki, et al.
Publicado: (2021)

Viral expansion after transfer is a primary driver of influenza A virus transmission bottlenecks
por: Holmes, Katie E., et al.
Publicado: (2023)

Incomplete influenza A virus genomes occur frequently but are readily complemented during localized viral spread
por: Jacobs, Nathan T., et al.
Publicado: (2019)

Collective interactions augment influenza A virus replication in a host-dependent manner
por: Phipps, Kara L., et al.
Publicado: (2020)

Influenza Virus Transmission Is Dependent on Relative Humidity and Temperature
por: Lowen, Anice C, et al.
Publicado: (2007)

Host factor Rab11a is critical for efficient assembly of influenza A virus genomic segments
por: Han, Julianna, et al.
Publicado: (2021)

It’s in the mix: Reassortment of segmented viral genomes
por: Lowen, Anice C.
Publicado: (2018)

Transmission of Influenza Virus in a Mammalian Host Is Increased by PB2 Amino Acids 627K or 627E/701N
por: Steel, John, et al.
Publicado: (2009)

Mutational Analyses of the Influenza A Virus Polymerase Subunit PA Reveal Distinct Functions Related and Unrelated to RNA Polymerase Activity
por: Liang, Yuhong, et al.
Publicado: (2012)

Influenza Virus Reassortment Is Enhanced by Semi-infectious Particles but Can Be Suppressed by Defective Interfering Particles
por: Fonville, Judith M., et al.
Publicado: (2015)

H5N8 and H7N9 packaging signals constrain HA reassortment with a seasonal H3N2 influenza A virus
por: White, Maria C., et al.
Publicado: (2019)

Animal Models for Influenza Virus Pathogenesis and Transmission
por: Bouvier, Nicole M., et al.
Publicado: (2010)

Transmission of Influenza Virus via Aerosols and Fomites in the Guinea Pig Model
por: Mubareka, Samira, et al.
Publicado: (2009)

Message in a bottle: mRNA vaccination for influenza
por: Shartouny, Jessica R., et al.
Publicado: (2022)

Filament-Producing Mutants of Influenza A/Puerto Rico/8/1934 (H1N1) Virus Have Higher Neuraminidase Activities than the Spherical Wild-Type
por: Seladi-Schulman, Jill, et al.
Publicado: (2014)

Influenza Virus Vaccine Based on the Conserved Hemagglutinin Stalk Domain
por: Steel, John, et al.
Publicado: (2010)

Transmission in the Guinea Pig Model
por: Lowen, Anice C., et al.
Publicado: (2014)

Role of helical structure and dynamics in oligoadenylate synthetase 1 (OAS1) mismatch tolerance and activation by short dsRNAs
por: Schwartz, Samantha L., et al.
Publicado: (2022)

The small genome segment of Bunyamwera orthobunyavirus harbours a single transcription-termination signal
por: Blakqori, Gjon, et al.
Publicado: (2012)

Influenza A virus reassortment in mammals gives rise to genetically distinct within-host subpopulations
por: Ganti, Ketaki, et al.
Publicado: (2022)

Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2
por: Opresko, Patricia L., et al.
Publicado: (2005)

Human noncoding RNA 886 (nc886) adopts two structurally distinct conformers that are functionally opposing regulators of PKR
por: Calderon, Brenda M., et al.
Publicado: (2017)

Mutations in the NS1 C-terminal tail do not enhance replication or virulence of the 2009 pandemic H1N1 influenza A virus
por: Hale, Benjamin G., et al.
Publicado: (2010)

Mutation L319Q in the PB1 Polymerase Subunit Improves Attenuation of a Candidate Live-Attenuated Influenza A Virus Vaccine
por: Nogales, Aitor, et al.
Publicado: (2022)

A novel RNA molecular signature for activation of 2′-5′ oligoadenylate synthetase-1
por: Vachon, Virginia K., et al.
Publicado: (2015)

Animal models for SARS-CoV-2
por: Lee, Chung-Young, et al.
Publicado: (2021)

Exclusion of latecomers yields a patchwork of viral subpopulations within hosts
por: Lowen, Anice C., et al.
Publicado: (2023)

Intra- and inter-host evolution of H9N2 influenza A virus in Japanese quail
por: Ferreri, Lucas M, et al.
Publicado: (2022)

Why Are CD8 T Cell Epitopes of Human Influenza A Virus Conserved?
por: Li, Zheng-Rong Tiger, et al.
Publicado: (2019)

Influenza A viruses are transmitted via the air from the nasal respiratory epithelium of ferrets
por: Richard, Mathilde, et al.
Publicado: (2020)

Recombinant SARS-CoV-2 genomes are currently circulating at low levels
por: VanInsberghe, David, et al.
Publicado: (2021)

Recombinant SARS-CoV-2 genomes circulated at low levels over the first year of the pandemic
por: VanInsberghe, David, et al.
Publicado: (2021)

Protective efficacy of influenza group 2 hemagglutinin stem-fragment immunogen vaccines
por: Sutton, Troy C., et al.
Publicado: (2017)

Genetic drift and purifying selection shape within-host influenza A virus populations during natural swine infections
por: VanInsberghe, David, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_eitnsq8lso53ck71fe3311ou61