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A pharmacokinetic model including arrival time for two inputs and compensating for varying applied flip-angle in dynamic gadoxetic acid-enhanced MR imaging

PURPOSE: Pharmacokinetic models facilitate assessment of properties of the micro-vascularization based on DCE-MRI data. However, accurate pharmacokinetic modeling in the liver is challenging since it has two vascular inputs and it is subject to large deformation and displacement due to respiration....

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Detalles Bibliográficos
Autores principales: Zhang, Tian, Runge, Jurgen H., Lavini, Cristina, Stoker, Jaap, van Gulik, Thomas, Cieslak, Kasia P., van Vliet, Lucas J., Vos, Frans M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695151/
https://www.ncbi.nlm.nih.gov/pubmed/31415613
http://dx.doi.org/10.1371/journal.pone.0220835