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Hyperglycemia acts in synergy with hypoxia to maintain the pro-inflammatory phenotype of macrophages
Diabetic foot ulcers (DFUs) are characterized by a chronic inflammation state which prevents cutaneous wound healing, and DFUs eventually lead to infection and leg amputation. Macrophages located in DFUs are locked in an pro-inflammatory phenotype. In this study, the effect of hyperglycemia and hypo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695165/ https://www.ncbi.nlm.nih.gov/pubmed/31415598 http://dx.doi.org/10.1371/journal.pone.0220577 |