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The impact of DNA methylation on the cancer proteome

Aberrant DNA methylation disrupts normal gene expression in cancer and broadly contributes to oncogenesis. We previously developed MethylMix, a model-based algorithmic approach to identify epigenetically regulated driver genes. MethylMix identifies genes where methylation likely executes a functiona...

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Detalles Bibliográficos
Autores principales: Magzoub, Majed Mohamed, Prunello, Marcos, Brennan, Kevin, Gevaert, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695193/
https://www.ncbi.nlm.nih.gov/pubmed/31356589
http://dx.doi.org/10.1371/journal.pcbi.1007245