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The impact of DNA methylation on the cancer proteome
Aberrant DNA methylation disrupts normal gene expression in cancer and broadly contributes to oncogenesis. We previously developed MethylMix, a model-based algorithmic approach to identify epigenetically regulated driver genes. MethylMix identifies genes where methylation likely executes a functiona...
Autores principales: | Magzoub, Majed Mohamed, Prunello, Marcos, Brennan, Kevin, Gevaert, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695193/ https://www.ncbi.nlm.nih.gov/pubmed/31356589 http://dx.doi.org/10.1371/journal.pcbi.1007245 |
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