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Dual Mechanisms of Action of Self-Delivering, Anti-HIV-1 FANA Oligonucleotides as a Potential New Approach to HIV Therapy

Currently, the most effective and durable therapeutic option for HIV-1 infection is combination antiretroviral therapy (cART). Although cART is powerful and can delay viral evolution of drug resistance for decades, it is associated with limitations, including an inability to eradicate the virus and...

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Detalles Bibliográficos
Autores principales: Takahashi, Mayumi, Li, Haitang, Zhou, Jiehua, Chomchan, Pritsana, Aishwarya, Veenu, Damha, Masad J., Rossi, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695270/
https://www.ncbi.nlm.nih.gov/pubmed/31394430
http://dx.doi.org/10.1016/j.omtn.2019.07.001