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Cysteine-based regulation of redox-sensitive Ras small GTPases

Reactive oxygen and nitrogen species (ROS and RNS, respectively) activate the redox-sensitive Ras small GTPases. The three canonical genes (HRAS, NRAS, and KRAS) are archetypes of the superfamily of small GTPases and are the most common oncogenes in human cancer. Oncogenic Ras is intimately linked t...

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Detalles Bibliográficos
Autores principales: Messina, Samantha, De Simone, Giovanna, Ascenzi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695279/
https://www.ncbi.nlm.nih.gov/pubmed/31386964
http://dx.doi.org/10.1016/j.redox.2019.101282