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An increase in plasma brain derived neurotrophic factor levels is related to n-3 polyunsaturated fatty acid efficacy in first episode schizophrenia: secondary outcome analysis of the OFFER randomized clinical trial

RATIONALE: N−3 polyunsaturated fatty acids (n−3 PUFA) influence multiple biochemical mechanisms postulated in the pathogenesis of schizophrenia that may influence BDNF synthesis. OBJECTIVES: A randomized placebo-controlled study was designed to compare the efficacy of a 26-week intervention composed...

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Detalles Bibliográficos
Autores principales: Pawełczyk, Tomasz, Grancow-Grabka, Marta, Trafalska, Elżbieta, Szemraj, Janusz, Żurner, Natalia, Pawełczyk, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695351/
https://www.ncbi.nlm.nih.gov/pubmed/31098654
http://dx.doi.org/10.1007/s00213-019-05258-4