Alternate subunit assembly diversifies the function of a bacterial toxin

Bacterial toxins with an AB(5) architecture consist of an active (A) subunit inserted into a ring-like platform comprised of five delivery (B) subunits. Salmonella Typhi, the cause of typhoid fever, produces an unusual A(2)B(5) toxin known as typhoid toxin. Here, we report that upon infection of hum...

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Detalles Bibliográficos
Autores principales: Fowler, Casey C., Stack, Gabrielle, Jiao, Xuyao, Lara-Tejero, Maria, Galán, Jorge E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695444/
https://www.ncbi.nlm.nih.gov/pubmed/31417089
http://dx.doi.org/10.1038/s41467-019-11592-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695444/
https://www.ncbi.nlm.nih.gov/pubmed/31417089
http://dx.doi.org/10.1038/s41467-019-11592-0

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