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Novel method for action potential measurements from intact cardiac monolayers with multiwell microelectrode array technology

The cardiac action potential (AP) is vital for understanding healthy and diseased cardiac biology and drug safety testing. However, techniques for high throughput cardiac AP measurements have been limited. Here, we introduce a novel technique for reliably increasing the coupling of cardiomyocyte syn...

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Detalles Bibliográficos
Autores principales: Hayes, Heather B., Nicolini, Anthony M., Arrowood, Colin A., Chvatal, Stacie A., Wolfson, David W., Cho, Hee Cheol, Sullivan, Denise D., Chal, Jérome, Fermini, Bernard, Clements, Mike, Ross, James D., Millard, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695445/
https://www.ncbi.nlm.nih.gov/pubmed/31417144
http://dx.doi.org/10.1038/s41598-019-48174-5