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The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature

Stl is a master repressor encoded by Staphylococcus aureus pathogenicity islands (SaPIs) that maintains integration of these elements in the bacterial chromosome. After infection or induction of a resident helper phage, SaPIs are de-repressed by specific interactions of phage proteins with Stl. SaPI...

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Detalles Bibliográficos
Autores principales: Ciges-Tomas, J. Rafael, Alite, Christian, Humphrey, Suzanne, Donderis, J., Bowring, Janine, Salvatella, Xavier, Penadés, José R., Marina, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695447/
https://www.ncbi.nlm.nih.gov/pubmed/31417084
http://dx.doi.org/10.1038/s41467-019-11504-2