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Design of high-order antibiotic combinations against M. tuberculosis by ranking and exclusion
Combinations of more than two drugs are routinely used for the treatment of pathogens and tumors. High-order combinations may be chosen due to their non-overlapping resistance mechanisms or for favorable drug interactions. Synergistic/antagonistic interactions occur when the combination has a higher...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695482/ https://www.ncbi.nlm.nih.gov/pubmed/31417151 http://dx.doi.org/10.1038/s41598-019-48410-y |