Cargando…

The NRON complex controls circadian clock function through regulated PER and CRY nuclear translocation

Post-translational regulation plays a central role in the circadian clock mechanism. However, nucleocytoplasmic translocation of core clock proteins, a key step in circadian timekeeping, is not fully understood. Earlier we found that the NRON scaffolding complex regulates nuclear translocation of NF...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Yool, Shen, Yang, Francey, Lauren J., Ramanathan, Chidambaram, Sehgal, Amita, Liu, Andrew C., Hogenesch, John B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695496/
https://www.ncbi.nlm.nih.gov/pubmed/31417156
http://dx.doi.org/10.1038/s41598-019-48341-8