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Modulation of immune responses in lentiviral vector-mediated gene transfer

Lentiviral vectors (LV) are widely used vehicles for gene transfer and therapy in pre-clinical animal models and clinical trials with promising safety and efficacy results. However, host immune responses against vector- and/or transgene-derived antigens remain a major obstacle to the success and bro...

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Detalles Bibliográficos
Autores principales: Annoni, Andrea, Gregori, Silvia, Naldini, Luigi, Cantore, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695505/
https://www.ncbi.nlm.nih.gov/pubmed/29735164
http://dx.doi.org/10.1016/j.cellimm.2018.04.012