Cargando…
Modulation of immune responses in lentiviral vector-mediated gene transfer
Lentiviral vectors (LV) are widely used vehicles for gene transfer and therapy in pre-clinical animal models and clinical trials with promising safety and efficacy results. However, host immune responses against vector- and/or transgene-derived antigens remain a major obstacle to the success and bro...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695505/ https://www.ncbi.nlm.nih.gov/pubmed/29735164 http://dx.doi.org/10.1016/j.cellimm.2018.04.012 |