Cargando…
Modulation of immune responses in lentiviral vector-mediated gene transfer
Lentiviral vectors (LV) are widely used vehicles for gene transfer and therapy in pre-clinical animal models and clinical trials with promising safety and efficacy results. However, host immune responses against vector- and/or transgene-derived antigens remain a major obstacle to the success and bro...
Autores principales: | Annoni, Andrea, Gregori, Silvia, Naldini, Luigi, Cantore, Alessio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695505/ https://www.ncbi.nlm.nih.gov/pubmed/29735164 http://dx.doi.org/10.1016/j.cellimm.2018.04.012 |
Ejemplares similares
-
WFH State‐of‐the‐art paper 2020: In vivo lentiviral vector gene therapy for haemophilia
por: Cantore, Alessio, et al.
Publicado: (2020) -
Liver gene therapy by lentiviral vectors reverses anti-factor IX pre-existing immunity in haemophilic mice
por: Annoni, Andrea, et al.
Publicado: (2013) -
Genome editing for scalable production of alloantigen‐free lentiviral vectors for in vivo gene therapy
por: Milani, Michela, et al.
Publicado: (2017) -
Laboratory-Scale Lentiviral Vector Production and Purification for Enhanced Ex Vivo and In Vivo Genetic Engineering
por: Soldi, Monica, et al.
Publicado: (2020) -
Lentiviral Vector Gene Transfer to Porcine Airways
por: Sinn, Patrick L, et al.
Publicado: (2012)