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Immunogenicity and Viral Shedding of Russian-Backbone, Seasonal, Trivalent, Live, Attenuated Influenza Vaccine in a Phase II, Randomized, Placebo-Controlled Trial Among Preschool-Aged Children in Urban Bangladesh

BACKGROUND: We evaluated a Russian-backbone, live, attenuated influenza vaccine (LAIV) for immunogenicity and viral shedding in a randomized, placebo-controlled trial among Bangladeshi children. METHODS: Healthy children received a single, intranasal dose of LAIV containing the 2011–2012 recommended...

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Detalles Bibliográficos
Autores principales: Lewis, Kristen D C, Ortiz, Justin R, Rahman, Mohammed Z, Levine, Min Z, Rudenko, Larisa, Wright, Peter F, Katz, Jacqueline M, Dally, Len, Rahman, Mustafizur, Isakova-Sivak, Irina, Ilyushina, Natalia A, Matyushenko, Victoria, Fry, Alicia M, Lindstrom, Stephen E, Bresee, Joseph S, Brooks, W Abdullah, Neuzil, Kathleen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695509/
https://www.ncbi.nlm.nih.gov/pubmed/30481272
http://dx.doi.org/10.1093/cid/ciy1003