Sustained suppression of IL-18 by employing a vaccine ameliorates intestinal inflammation in TNBS-induced murine colitis

AIM: To develop IL-18 peptide-based virus-like particle vaccines that elicit autoantibodies against IL-18 and to evaluate the in vivo effects of the vaccines in murine colitis. METHODS: Recombinant IL-18 vaccines were constructed, and the effects of the vaccines were evaluated in trinitrobenzene sul...

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Detalles Bibliográficos
Autores principales: Guan, Qingdong, Warrington, Richard, Moreno, Sem, Qing, Gefei, Weiss, Carolyn, Peng, Zhikang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2019
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695525/
https://www.ncbi.nlm.nih.gov/pubmed/31428451
http://dx.doi.org/10.2144/fsoa-2018-0125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695525/
https://www.ncbi.nlm.nih.gov/pubmed/31428451
http://dx.doi.org/10.2144/fsoa-2018-0125

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